Type 2 Diabetes

Overview 
Type 2 diabetes is a common condition that causes the level of sugar (glucose) in the blood to become too high. It can cause symptoms like excessive thirst, needing to pee a lot and tiredness. It can also increase your risk of getting serious problems with your eyes, heart and nerves. It's a lifelong condition that can affect your everyday life. You may need to change your diet, take medicines and have regular check-ups.

Causes
It's caused by problems with a chemical in the body (hormone) called insulin. It's often linked to being overweight or inactive, or having a family history of type 2 diabetes.

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Research Summary
 
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759

Diabetes II trials open globally

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Global trials - phase

Phase indicates how far along the treatment is in the development process. Phase 1 indicates very early, phase 4 is later.

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42

Diabetes II trials open in the UK

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9,508

Participants required for UK studies

Global trials - interventions

Intervention is the type of treatment that will be being tested during the trial.

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Nye Spotlight Trials
Evaluation of Diabetes and WELLbeing Programme
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Study type: interventional

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400 estimated participants

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Recruitment ends 2023-03-31

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  • Medway Community Healthcare, Gillingham

  • Blackthorn Trust, Maidstone

About the study

This study evaluates the impact of 'DWELL' - a 12-week psycho-social education programme designed to help people with type 2 diabetes to better self-manage...

Eligibility

Inclusion Criteria:

  • Clinical diagnosis of type 2 diabetes

  • Over the age of 18

Exclusion Criteria:

  • Under the age of 18...

Prevalence and Determinants of Subclinical Cardiovascular Dysfunction in Adults With Type 2 Diabetes Mellitus
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Study type: Observational

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200 estimated participants

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Recruitment ends 2022-06-01

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University of Leicester, Leicester

About the study

Background: Heart failure is a major cause of morbidity and mortality in diabetes mellitus, but its pathophysiology is poorly understood.

Aim: To determine the prevalence and determinants...

Eligibility

Inclusion Criteria:

  • Participant is willing and able to give informed consent for participation in the study.

  • Male or Female, aged ≥18 and ≤75 years.

  • Diagnosed with Stable type 2 diabetes (determined...

Longitudinal Assessment of Multiple Organs in Patients With Type 2 Diabetes
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Study type: Observational

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150 estimated participants

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Recruitment ends 2026-09-30

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  • Aintree University Hospital NHS Foundation Trust, Liverpool

  • Oxford University Hospitals NHS Foundation Trust, Oxford

  • Royal Free Hospital NHS Foundation Trust, London

About the study

MODIFY study is a multi-centre prospective, longitudinal, observational cohort study which aims to recruit 150 adult patients with type 2 diabetes recruited...

Eligibility

Inclusion Criteria:

  • Male or female over 18 years of age and diagnosed with type 2 diabetes.

  • Participant currently taking glucose lowering therapy.

  • Participant willing and able to give informed...

Assessment of the Impact of a Personalised Nutrition Intervention in Impaired Glucose Regulation
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Study type: interventional

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180 estimated participants

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Recruitment ends 2022-08-01

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Imperial Clinical Research Facility, London

About the study

This study will determine if DNA-based dietary guidelines can improve glucose regulation in pre-diabetic individuals significantly more than standard dietary...

Eligibility

Inclusion Criteria:

  • Provision of signed and dated informed consent form

  • Adults over 18 years of age

  • Impaired glucose regulation including impaired...